Prescription drug coverage is one of the most important—but most misunderstood—parts of a health insurance plan. Whether you’re picking up antibiotics or managing a chronic condition, knowing how your plan covers medications can save you a ton of stress and money.
Here’s what you need to know about formularies, drug tiers, and how to navigate denials.
What Is a Formulary?
A formulary is the list of prescription drugs your health insurance plan covers. It includes both generic and brand-name medications, organized by category and cost level.
Insurance companies work with pharmacy benefit managers (PBMs) to decide which drugs to include and how much they’ll cost you. The goal is to balance effective treatment with affordability—for both you and the insurer.
Plans usually update their formularies once or twice a year, so the list can change.
Types of Formularies
Open formulary: Covers a broad range of medications, with some exclusions.
Closed formulary: Only covers drugs on the list—others are not paid for unless an exception is granted.
Always check the most recent formulary from your insurer before filling a new prescription.
What Are Drug Tiers?
Formularies are divided into tiers, which determine how much you’ll pay out of pocket. The higher the tier, the more expensive the medication typically is.
Here’s a breakdown of common formulary tiers in 2025:
Prescription Drug Tier Comparison
Tier | Type of Drug | Typical Copay or Coinsurance | Example Medications |
---|---|---|---|
Tier 1 | Generic drugs | Lowest cost ($10–$20 copay) | Lisinopril, Metformin |
Tier 2 | Preferred brand-name drugs | Moderate cost ($30–$60 copay) | Lipitor, Zoloft |
Tier 3 | Non-preferred brand-name drugs | Higher cost ($75–$100+) | Xarelto, Trulicity |
Tier 4 | Specialty drugs | Highest cost (coinsurance %) | Humira, Ozempic |
Tier 5 | Rare/exclusive use drugs | Custom pricing or full cost | Limited to certain plans |
The actual costs can vary based on your plan’s structure (copay vs coinsurance) and whether you’ve met your deductible.
How to Find Out if Your Medication Is Covered
Before heading to the pharmacy, here’s how to check if your prescription is on the formulary:
Log in to your insurer’s portal.
Search the formulary tool for the exact name of your medication.
Check what tier it’s in, whether it requires prior authorization, or if there are preferred alternatives.
If your medication isn’t listed, or is in a high-cost tier, you may have options to reduce costs.
Prior Authorization and Step Therapy
Some drugs require prior authorization, meaning your doctor must get approval from your insurance before the plan will cover the medication. This process ensures the drug is medically necessary.
Others may require step therapy, where you have to try a lower-cost medication first before the insurer covers a more expensive one.
These requirements can slow things down, but they’re often negotiable with proper documentation from your doctor.
Generic vs Brand Name Drugs
Choosing a generic drug when possible can dramatically lower your costs. Generics are FDA-approved, contain the same active ingredients, and are usually in Tier 1.
Brand-name drugs may be placed in higher tiers unless no generic equivalent exists. If you’re prescribed a brand drug, always ask if a generic alternative is available.
Appealing a Drug Denial
If your insurance denies coverage for a medication, you’re not out of options. Here’s how to fight back:
Steps to Appeal a Drug Denial
Request a written denial letter. This explains why the drug wasn’t approved.
Talk to your doctor. They can help submit a letter of medical necessity.
File an internal appeal. Follow the instructions in your plan’s denial letter.
Request an external review. If the internal appeal is denied, you can ask an independent reviewer to evaluate the case.
Some states also have consumer assistance programs that can help you through the process.
Using a Mail-Order Pharmacy
Many insurance plans offer savings through mail-order pharmacies, especially for long-term medications. These services typically deliver a 90-day supply and can lower your per-pill cost.
Just make sure your medication is eligible, and always check shipping times to avoid running out.
Extra Help for High-Cost Medications
If you’re prescribed a drug that costs hundreds or even thousands per month, don’t panic. Here are some support options:
Manufacturer copay cards – Often available for brand-name drugs
Patient assistance programs (PAPs) – Run by nonprofits or drug companies
State pharmaceutical assistance – Especially helpful for seniors or low-income households
Health Savings Accounts (HSAs) – Can be used tax-free to cover prescription costs
Your doctor or pharmacist may also be able to recommend lower-cost alternatives.
Tips for Managing Drug Costs
Always ask if a generic version is available
Compare prices using pharmacy tools like GoodRx
Stick with in-network pharmacies
Use your plan’s preferred drug list
Refill early to avoid emergency costs
Consider a 90-day supply for chronic meds
Being proactive can make a big difference in how much you spend at the pharmacy.
Understanding Prescription Drug Coverage Makes a Difference
Health insurance does cover prescription drugs—but not all drugs are treated equally. Between formularies, tiers, prior authorizations, and appeal processes, there’s a lot to juggle. But understanding the system helps you get the medications you need without breaking the bank.
Take time to review your plan’s drug list and ask questions when something isn’t clear. A little research now can save you a lot of money—and frustration—later on.
The Bottom Line
Both HMO and PPO plans offer unique benefits, and the right choice depends on your healthcare needs, budget, and personal preferences. If you prioritize lower costs and don’t mind network restrictions, an HMO might be the best option. However, if you want greater freedom to choose providers and access specialists without referrals, a PPO could be a better fit. Carefully weigh your priorities and compare plan details to make the best decision for your health and financial well-being.